No. Certifications and studies show that phade® is not harmful to marine life. phade® has passed rigorous testing for eco-toxicity as part of its numerous certifications. Further, PHA has been used in several applications where it is intentionally introduced to marine life (as a carrier for antibiotics) and humans (for medical applications). A University study* conducted in 2019 testing small quantities of PHA introduced to both fish and livestock found that fish actually grew larger, faster and with better overall digestive health than marine life that did not ingest PHA.
*Microbial Poly-3-Hydroxybutyrate (PHB) as a Feed Additive for Fishes and Piglets, May 2019, Biotechnology Journal 14(12):1900132 DOI:10.1002/biot.201900132